AIIMS Develops India’s First High-Precision TEM Diagnostic Method for Primary Ciliary Dyskinesia

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Introduction: A Breakthrough in Rare Disease Diagnostics In a significant leap for India’s healthcare and diagnostic capabilities, scientists from the All India Institute of Medical Sciences (AIIMS), New Delhi , have developed a first-of-its-kind diagnostic method for identifying Primary Ciliary Dyskinesia (PCD) — a rare genetic condition that affects the respiratory system. This new method utilizes Transmission Electron Microscopy (TEM) to offer diagnostic precision 640 times greater than conventional techniques. What is Primary Ciliary Dyskinesia? Primary Ciliary Dyskinesia (PCD) is a rare and underdiagnosed genetic disorder that impairs the structure and function of motile cilia — hair-like structures that line the respiratory tract. These cilia are crucial for clearing mucus and pathogens. Dysfunction leads to chronic respiratory infections, bronchiectasis, sinusitis , and in some cases, infertility and situs inversus . India’s First TEM-Based PCD Diagnostic Protocol ...
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